G9a functions as a molecular scaffold for assembly of transcriptional coactivators on a subset of Glucocorticoid Receptor target genes

Histone H3 lysine-9 methyltransferase G9a/EHMT2/KMT1C is a key corepressor of gene expression. However, activation of a limited number of genes by G9a (independent of its catalytic activity) has also been observed, although the precise molecular mechanisms are unknown. By using RNAi in combination w...

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Bibliografske podrobnosti
Main Authors: Bittencourt, Danielle, Wu, Dai-Ying, Jeong, Kwang Won, Gerke, Daniel S., Herviou, Laurie, Ianculescu, Irina, Chodankar, Rajas, Siegmund, Kimberly D., Stallcup, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511704/
https://ncbi.nlm.nih.gov/pubmed/23151507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1211803109
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