Akt2 Kinase Suppresses Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH)-mediated Apoptosis in Ovarian Cancer Cells via Phosphorylating GAPDH at Threonine 237 and Decreasing Its Nuclear Translocation

Protein kinase B (Akt) plays important roles in regulation of cell growth and survival, but while many aspects of its mechanism of action are known, there are potentially additional regulatory events that remain to be discovered. Here we detected a 36-kDa protein that was co-immunoprecipitated with...

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Hlavní autoři: Huang, Qiaojia, Lan, Fenghua, Zheng, Zhiyong, Xie, Feilai, Han, Junyong, Dong, Lihong, Xie, Yanchuan, Zheng, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234938/
https://ncbi.nlm.nih.gov/pubmed/21979951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.296905
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