Akt2 Kinase Suppresses Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH)-mediated Apoptosis in Ovarian Cancer Cells via Phosphorylating GAPDH at Threonine 237 and Decreasing Its Nuclear Translocation

Protein kinase B (Akt) plays important roles in regulation of cell growth and survival, but while many aspects of its mechanism of action are known, there are potentially additional regulatory events that remain to be discovered. Here we detected a 36-kDa protein that was co-immunoprecipitated with...

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Detalhes bibliográficos
Main Authors: Huang, Qiaojia, Lan, Fenghua, Zheng, Zhiyong, Xie, Feilai, Han, Junyong, Dong, Lihong, Xie, Yanchuan, Zheng, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234938/
https://ncbi.nlm.nih.gov/pubmed/21979951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.296905
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