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Regulation of Cellular Levels of Sprouty2 Protein by Prolyl Hydroxylase Domain and von Hippel-Lindau Proteins

Sprouty (Spry) proteins modulate the actions of receptor tyrosine kinases during development and tumorigenesis. Decreases in cellular levels of Spry, especially Sprouty2 (Spry2), have been implicated in the growth and progression of tumors of the breast, prostate, lung, and liver. During development...

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Autores principales: Anderson, Kimberly, Nordquist, Kyle A., Gao, Xianlong, Hicks, Kristin C., Zhai, Bo, Gygi, Steven P., Patel, Tarun B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234935/
https://ncbi.nlm.nih.gov/pubmed/22006925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.303222
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