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Regulation of Cellular Levels of Sprouty2 Protein by Prolyl Hydroxylase Domain and von Hippel-Lindau Proteins

Sprouty (Spry) proteins modulate the actions of receptor tyrosine kinases during development and tumorigenesis. Decreases in cellular levels of Spry, especially Sprouty2 (Spry2), have been implicated in the growth and progression of tumors of the breast, prostate, lung, and liver. During development...

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Hlavní autoři: Anderson, Kimberly, Nordquist, Kyle A., Gao, Xianlong, Hicks, Kristin C., Zhai, Bo, Gygi, Steven P., Patel, Tarun B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234935/
https://ncbi.nlm.nih.gov/pubmed/22006925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.303222
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