Corepressor Protein CDYL Functions as a Molecular Bridge between Polycomb Repressor Complex 2 and Repressive Chromatin Mark Trimethylated Histone Lysine 27

Polycomb group proteins play essential roles in transcriptional regulation of multiple gene families involved in various pathophysiological processes. It is believed that Polycomb Repressive Complex 2 (PRC2) is targeted to chromatin by the EED subunit to methylate histone H3 lysine 27 (H3K27), leadi...

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Hlavní autoři: Zhang, Yu, Yang, Xiaohan, Gui, Bin, Xie, Guojia, Zhang, Di, Shang, Yongfeng, Liang, Jing
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
DNA and Chromosomes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234934/
https://ncbi.nlm.nih.gov/pubmed/22009739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.271064
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