Transthiocarbamoylation of Proteins by Thiolated Isothiocyanates

Isothiocyanates, membrane-permeable electrophiles that form adducts with thiols, have been suggested to have important medical benefits. Here we shed light on isothiocyanate-thiol conjugates and studied their electrophilic potential transferring an isothiocyanate moiety to cellular proteins. When we...

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Bibliografiske detaljer
Main Authors: Shibata, Takahiro, Kimura, Yuuki, Mukai, Akihiro, Mori, Hitoshi, Ito, Sohei, Asaka, Yukio, Oe, Sho, Tanaka, Hiroshi, Takahashi, Takashi, Uchida, Koji
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234917/
https://ncbi.nlm.nih.gov/pubmed/21998322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.308049
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