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Progesterone Receptor Inhibits Proliferation of Human Breast Cancer Cells via Induction of MAPK Phosphatase 1 (MKP-1/DUSP1)

The roles of progesterone (P(4)) and of progesterone receptor (PR) in development and pathogenesis of breast cancer remain unclear. In this study, we observed that treatment of T47D breast cancer cells with progestin antagonized effects of fetal bovine serum (FBS) to stimulate cell proliferation, wh...

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Detalhes bibliográficos
Main Authors: Chen, Chien-Cheng, Hardy, Daniel B., Mendelson, Carole R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234857/
https://ncbi.nlm.nih.gov/pubmed/22020934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.295865
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