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Progesterone Receptor Inhibits Proliferation of Human Breast Cancer Cells via Induction of MAPK Phosphatase 1 (MKP-1/DUSP1)

The roles of progesterone (P(4)) and of progesterone receptor (PR) in development and pathogenesis of breast cancer remain unclear. In this study, we observed that treatment of T47D breast cancer cells with progestin antagonized effects of fetal bovine serum (FBS) to stimulate cell proliferation, wh...

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Библиографические подробности
Главные авторы: Chen, Chien-Cheng, Hardy, Daniel B., Mendelson, Carole R.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234857/
https://ncbi.nlm.nih.gov/pubmed/22020934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.295865
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