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Inhibitory Member of the Apoptosis-stimulating Proteins of the p53 Family (iASPP) Interacts with Protein Phosphatase 1 via a Noncanonical Binding Motif

Although kinase mutations have been identified in various human diseases, much less is known about protein phosphatases. Here, we show that all apoptosis-stimulating proteins of p53 (ASPP) family members can bind protein phosphatase 1 (PP1) via two distinct interacting motifs. ASPP2 interacts with P...

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Detalhes bibliográficos
Main Authors: Llanos, Susana, Royer, Christophe, Lu, Min, Bergamaschi, Daniele, Lee, Wen Hwa, Lu, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234852/
https://ncbi.nlm.nih.gov/pubmed/21998301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.270751
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