ASPP1 and ASPP2: Common Activators of p53 Family Members

We recently showed that ASPP1 and ASPP2 stimulate the apoptotic function of p53. We show here that ASPP1 and ASPP2 also induce apoptosis independently of p53. By binding to p63 and p73 in vitro and in vivo, ASPP1 and ASPP2 stimulate the transactivation function of p63 and p73 on the promoters of Bax...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bergamaschi, Daniele, Samuels, Yardena, Jin, Boquan, Duraisingham, Sai, Crook, Tim, Lu, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC321425/
https://ncbi.nlm.nih.gov/pubmed/14729977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.3.1341-1350.2004
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados