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The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1

Tight junctions are cell-cell contacts that regulate the paracellular flux of solutes and prevent pathogen entry across cell layers. The assembly and permeability of this barrier are dependent on the zonula occludens (ZO) membrane-associated guanylate kinase (MAGUK) proteins ZO-1, -2, and -3. MAGUK...

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Detalles Bibliográficos
Main Authors: Nomme, Julian, Fanning, Alan S., Caffrey, Michael, Lye, Ming F., Anderson, James M., Lavie, Arnon
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234847/
https://ncbi.nlm.nih.gov/pubmed/22030391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.304089
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