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Structural Basis for Partial Redundancy in a Class of Transcription Factors, the LIM Homeodomain Proteins, in Neural Cell Type Specification

Combinations of LIM homeodomain proteins form a transcriptional “LIM code” to direct the specification of neural cell types. Two paralogous pairs of LIM homeodomain proteins, LIM homeobox protein 3/4 (Lhx3/Lhx4) and Islet-1/2 (Isl1/Isl2), are expressed in developing ventral motor neurons. Lhx3 and I...

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Detalhes bibliográficos
Main Authors: Gadd, Morgan S., Bhati, Mugdha, Jeffries, Cy M., Langley, David B., Trewhella, Jill, Guss, J. Mitchell, Matthews, Jacqueline M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234805/
https://ncbi.nlm.nih.gov/pubmed/22025611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.248559
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