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The Motif of Human Cardiac Myosin-binding Protein C Is Required for Its Ca(2+)-dependent Interaction with Calmodulin

The N-terminal modules of cardiac myosin-binding protein C (cMyBP-C) play a regulatory role in mediating interactions between myosin and actin during heart muscle contraction. The so-called “motif,” located between the second and third immunoglobulin modules of the cardiac isoform, is believed to mo...

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Detalles Bibliográficos
Main Authors: Lu, Yanling, Kwan, Ann H., Jeffries, Cy M., Guss, J. Mitchell, Trewhella, Jill
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438991/
https://ncbi.nlm.nih.gov/pubmed/22801425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.383299
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