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The Fbw7 Tumor Suppressor Regulates Nuclear Factor E2-related Factor 1 Transcription Factor Turnover through Proteasome-mediated Proteolysis

Nuclear factor E2-related factor 1 (Nrf1) is a basic leucine zipper transcription factor that plays important roles in cellular stress response and development. Currently, the mechanism regulating Nrf1 expression is poorly understood. We report here that Nrf1 is a short-lived protein that is targete...

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Detalhes bibliográficos
Main Authors: Biswas, Madhurima, Phan, Diane, Watanabe, Momoko, Chan, Jefferson Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234752/
https://ncbi.nlm.nih.gov/pubmed/21953459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253807
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