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Glycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1

Nuclear factor E2-related factor-1 (Nrf1) is a basic leucine zipper transcription factor that is known to regulate antioxidant and cytoprotective gene expression. It was recently shown that Nrf1 is regulated by SCF-Fbw7 ubiquitin ligase. However our knowledge of upstream signals that targets Nrf1 fo...

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Detalhes bibliográficos
Main Authors: Biswas, Madhurima, Kwong, Erick K., Park, Eujean, Nagra, Parminder, Chan, Jefferson Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186750/
https://ncbi.nlm.nih.gov/pubmed/23623971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2013.04.013
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