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Identification of Small Molecule Inhibitors of Phosphatidylinositol 3-Kinase and Autophagy

Macroautophagy (hereafter autophagy) is a lysosomal catabolic pathway that controls cellular homeostasis and survival. It has recently emerged as an attractive target for the treatment of a variety of degenerative diseases and cancer. The targeting of autophagy has, however, been hampered by the lac...

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Detalhes bibliográficos
Main Authors: Farkas, Thomas, Daugaard, Mads, Jäättelä, Marja
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234715/
https://ncbi.nlm.nih.gov/pubmed/21930714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269134
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