Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells.
The stability locus parB+ of plasmid R1 has been found to specify a unique type of plasmid maintenance function. Two genes, hok (host killing) and sok (suppressor of killing), are required for the stabilizing activity. The hok gene encodes a highly toxic gene product, whose overexpression causes a r...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1986
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3517851/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.10.3116 |
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