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Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells.

The stability locus parB+ of plasmid R1 has been found to specify a unique type of plasmid maintenance function. Two genes, hok (host killing) and sok (suppressor of killing), are required for the stabilizing activity. The hok gene encodes a highly toxic gene product, whose overexpression causes a r...

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Main Authors: Gerdes, K, Rasmussen, P B, Molin, S
Formato: Artigo
Idioma:Inglês
Publicado: 1986
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC323463/
https://ncbi.nlm.nih.gov/pubmed/3517851
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