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Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cells.

The stability locus parB+ of plasmid R1 has been found to specify a unique type of plasmid maintenance function. Two genes, hok (host killing) and sok (suppressor of killing), are required for the stabilizing activity. The hok gene encodes a highly toxic gene product, whose overexpression causes a r...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Gerdes, K, Rasmussen, P B, Molin, S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1986
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323463/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3517851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.10.3116
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