Streptococcus pneumoniae in Biofilms Are Unable to Cause Invasive Disease Due to Altered Virulence Determinant Production

It is unclear whether Streptococcus pneumoniae in biofilms are virulent and contribute to development of invasive pneumococcal disease (IPD). Using electron microscopy we confirmed the development of mature pneumococcal biofilms in a continuous-flow-through line model and determined that biofilm for...

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Detalhes bibliográficos
Main Authors: Sanchez, Carlos J., Kumar, Nikhil, Lizcano, Anel, Shivshankar, Pooja, Dunning Hotopp, Julie C., Jorgensen, James H., Tettelin, Hervé, Orihuela, Carlos J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234282/
https://ncbi.nlm.nih.gov/pubmed/22174882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028738
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