Streptococcus pneumoniae in Biofilms Are Unable to Cause Invasive Disease Due to Altered Virulence Determinant Production

It is unclear whether Streptococcus pneumoniae in biofilms are virulent and contribute to development of invasive pneumococcal disease (IPD). Using electron microscopy we confirmed the development of mature pneumococcal biofilms in a continuous-flow-through line model and determined that biofilm for...

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Autori principali: Sanchez, Carlos J., Kumar, Nikhil, Lizcano, Anel, Shivshankar, Pooja, Dunning Hotopp, Julie C., Jorgensen, James H., Tettelin, Hervé, Orihuela, Carlos J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234282/
https://ncbi.nlm.nih.gov/pubmed/22174882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028738
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