Streptococcus pneumoniae in Biofilms Are Unable to Cause Invasive Disease Due to Altered Virulence Determinant Production

It is unclear whether Streptococcus pneumoniae in biofilms are virulent and contribute to development of invasive pneumococcal disease (IPD). Using electron microscopy we confirmed the development of mature pneumococcal biofilms in a continuous-flow-through line model and determined that biofilm for...

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Bibliografische gegevens
Hoofdauteurs: Sanchez, Carlos J., Kumar, Nikhil, Lizcano, Anel, Shivshankar, Pooja, Dunning Hotopp, Julie C., Jorgensen, James H., Tettelin, Hervé, Orihuela, Carlos J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234282/
https://ncbi.nlm.nih.gov/pubmed/22174882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028738
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