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Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation.

In an earlier study it was discovered that when Friend erythroleukemia cells (FELC) were exposed to a variety of chemical agents capable of inducing differentiation, their DNA underwent genome-wide transient demethylation. In an attempt to elucidate the biochemical mechanism responsible for this phe...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Razin, A, Szyf, M, Kafri, T, Roll, M, Giloh, H, Scarpa, S, Carotti, D, Cantoni, G L
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323399/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3458243/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.9.2827
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