Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation.
In an earlier study it was discovered that when Friend erythroleukemia cells (FELC) were exposed to a variety of chemical agents capable of inducing differentiation, their DNA underwent genome-wide transient demethylation. In an attempt to elucidate the biochemical mechanism responsible for this phe...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1986
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323399/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3458243/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.9.2827 |
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