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Replacement of 5-methylcytosine by cytosine: a possible mechanism for transient DNA demethylation during differentiation.

In an earlier study it was discovered that when Friend erythroleukemia cells (FELC) were exposed to a variety of chemical agents capable of inducing differentiation, their DNA underwent genome-wide transient demethylation. In an attempt to elucidate the biochemical mechanism responsible for this phe...

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Hlavní autoři: Razin, A, Szyf, M, Kafri, T, Roll, M, Giloh, H, Scarpa, S, Carotti, D, Cantoni, G L
Médium: Artigo
Jazyk:Inglês
Vydáno: 1986
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC323399/
https://ncbi.nlm.nih.gov/pubmed/3458243
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