Antiviral effect of an oligo(nucleoside methylphosphonate) complementary to the splice junction of herpes simplex virus type 1 immediate early pre-mRNAs 4 and 5.

Selective inhibition of regulatory immediate early (IE) genes of herpes simplex virus type 1 (HSV-1) should inhibit virus growth. Treatment of HSV-1-infected cells with the oligo(nucleoside methylphosphonate) d(TpCCTCCTG) (deoxynucleoside methylphosphonate residues in italic), which is complementary...

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Bibliografische gegevens
Hoofdauteurs: Smith, C C, Aurelian, L, Reddy, M P, Miller, P S, Ts'o, P O
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1986
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC323391/
https://ncbi.nlm.nih.gov/pubmed/3010316
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