Metabolic activation and detoxication of nephrotoxic cysteine and homocysteine S-conjugates.

S-(1,2-Dichlorovinyl)-L-homocysteine (DCVHcy), an analogue of the nephrotoxin S-(1,2-dichlorovinyl)-L-cysteine (DCVCys), is a much more potent nephrotoxin than DCVCys both in vivo and in isolated renal proximal tubular cells. S-(1,2-Dichlorovinyl)-DL-alpha-methylhomocysteine, at equimolar doses rela...

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Bibliografske podrobnosti
Main Authors: Elfarra, A A, Lash, L H, Anders, M W
Format: Artigo
Jezik:Inglês
Izdano: 1986
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC323360/
https://ncbi.nlm.nih.gov/pubmed/3458225
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