Metabolic activation and detoxication of nephrotoxic cysteine and homocysteine S-conjugates.

S-(1,2-Dichlorovinyl)-L-homocysteine (DCVHcy), an analogue of the nephrotoxin S-(1,2-dichlorovinyl)-L-cysteine (DCVCys), is a much more potent nephrotoxin than DCVCys both in vivo and in isolated renal proximal tubular cells. S-(1,2-Dichlorovinyl)-DL-alpha-methylhomocysteine, at equimolar doses rela...

詳細記述

保存先:
書誌詳細
主要な著者: Elfarra, A A, Lash, L H, Anders, M W
フォーマット: Artigo
言語:Inglês
出版事項: 1986
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC323360/
https://ncbi.nlm.nih.gov/pubmed/3458225
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