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Pancreatic expression of human insulin gene in transgenic mice.
We have investigated the possibility of obtaining integration and expression of a native human gene in transgenic mice. An 11-kilobase (kb) human chromosomal DNA fragment including the insulin gene (1430 base pairs) was microinjected into fertilized mouse eggs. This fragment was present in the genom...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
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| Päätekijät: | , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
1986
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323328/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3517871/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.8.2511 |
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