cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide.
Membrane-permeant cAMP derivatives (dibutyryl- and 8-bromo-cAMP) increase gap-junctional conductance within minutes when applied to voltage-clamped pairs of rat hepatocytes. Glucagon also increases junctional conductances, but the response has a more rapid onset and is more rapidly reversible. The g...
Saved in:
| Published in: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1986
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323320/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3010311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.8.2473 |
| Tags: |
No Tags, Be the first to tag this record!
|