cAMP increases junctional conductance and stimulates phosphorylation of the 27-kDa principal gap junction polypeptide.

Membrane-permeant cAMP derivatives (dibutyryl- and 8-bromo-cAMP) increase gap-junctional conductance within minutes when applied to voltage-clamped pairs of rat hepatocytes. Glucagon also increases junctional conductances, but the response has a more rapid onset and is more rapidly reversible. The g...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Saez, J C, Spray, D C, Nairn, A C, Hertzberg, E, Greengard, P, Bennett, M V
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1986
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323320/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3010311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.8.2473
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