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Cholesterol Depletion of Hepatoma Cells Impairs Hepatitis B Virus Envelopment by Altering the Topology of the Large Envelope Protein

Previous reports have shown that cholesterol depletion of the membrane envelope of the hepatitis B virus (HBV) impairs viral infection of target cells. A potential function of this lipid in later steps of the viral life cycle remained controversial, with secretion of virions and subviral particles (...

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Detalhes bibliográficos
Main Authors: Dorobantu, Cristina, Macovei, Alina, Lazar, Catalin, Dwek, Raymond A., Zitzmann, Nicole, Branza-Nichita, Norica
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233160/
https://ncbi.nlm.nih.gov/pubmed/21994451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05423-11
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