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Activation of ERAD Pathway by Human Hepatitis B Virus Modulates Viral and Subviral Particle Production

Hepatitis B virus (HBV) belongs to the Hepadnaviridae family of enveloped DNA viruses. It was previously shown that HBV can induce endoplasmic reticulum (ER) stress and activate the IRE1-XBP1 pathway of the unfolded protein response (UPR), through the expression of the viral regulatory protein X (HB...

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Hlavní autoři: Lazar, Catalin, Macovei, Alina, Petrescu, Stefana, Branza-Nichita, Norica
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3312915/
https://ncbi.nlm.nih.gov/pubmed/22461906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034169
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