Cloning and sequence determination of a human rheumatoid factor light-chain gene.

The contribution of germ-line variable regions to autoantibody formation in humans is poorly understood. To study the gene structure of a human autoantibody, chronic lymphatic leukemia (CLL) cells from a patient with an IgM anti-IgG (rheumatoid factor, RF) paraprotein were utilized. The rearranged i...

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Detalhes bibliográficos
Main Authors: Jirik, F R, Sorge, J, Fong, S, Heitzmann, J G, Curd, J G, Chen, P P, Goldfien, R, Carson, D A
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC323258/
https://ncbi.nlm.nih.gov/pubmed/3083417
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