Cloning and sequence determination of a human rheumatoid factor light-chain gene.
The contribution of germ-line variable regions to autoantibody formation in humans is poorly understood. To study the gene structure of a human autoantibody, chronic lymphatic leukemia (CLL) cells from a patient with an IgM anti-IgG (rheumatoid factor, RF) paraprotein were utilized. The rearranged i...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1986
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323258/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3083417/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.7.2195 |
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