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Integrative nucleophosmin mutation-associated microRNA and gene expression pattern analysis identifies novel microRNA - target gene interactions in acute myeloid leukemia

BACKGROUND: MicroRNAs are regulators of gene expression, which act mainly by decreasing mRNA levels of their multiple targets. Deregulated microRNA expression has been shown for acute myeloid leukemia, a disease also characterized by altered gene expression associated with distinct genomic aberratio...

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Autori principali: Russ, Annika C., Sander, Sandrine, Lück, Sonja C., Lang, Katharina M., Bauer, Marion, Rücker, Frank G., Kestler, Hans A., Schlenk, Richard F., Döhner, Hartmut, Holzmann, Karlheinz, Döhner, Konstanze, Bullinger, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232260/
https://ncbi.nlm.nih.gov/pubmed/21880628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.046888
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