The NOTCH pathway contributes to cell fate decision in myelopoiesis

BACKGROUND: Controversy persists regarding the role of Notch signaling in myelopoiesis. We have used genetic approaches, employing two Notch zebrafish mutants deadly seven (DES) and beamter (BEA) with disrupted function of notch1a and deltaC, respectively, and Notch1a morphants to analyze the develo...

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Autori principali: Bugeon, Laurence, Taylor, Harriet B., Progatzky, Fränze, Lin, Michelle I., Ellis, Charles D., Welsh, Natalie, Smith, Emma, Vargesson, Neil, Gray, Caroline, Renshaw, Stephen A., Chico, Timothy J. A., Zon, Leonard I., Lamb, Jonathan, Dallman, Margaret J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2011
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232256/
https://ncbi.nlm.nih.gov/pubmed/21933862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.044115
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