The NOTCH pathway contributes to cell fate decision in myelopoiesis

BACKGROUND: Controversy persists regarding the role of Notch signaling in myelopoiesis. We have used genetic approaches, employing two Notch zebrafish mutants deadly seven (DES) and beamter (BEA) with disrupted function of notch1a and deltaC, respectively, and Notch1a morphants to analyze the develo...

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Bibliografiska uppgifter
Huvudupphovsmän: Bugeon, Laurence, Taylor, Harriet B., Progatzky, Fränze, Lin, Michelle I., Ellis, Charles D., Welsh, Natalie, Smith, Emma, Vargesson, Neil, Gray, Caroline, Renshaw, Stephen A., Chico, Timothy J. A., Zon, Leonard I., Lamb, Jonathan, Dallman, Margaret J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Ferrata Storti Foundation 2011
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232256/
https://ncbi.nlm.nih.gov/pubmed/21933862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.044115
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