Expression, purification and preliminary crystallographic analysis of Rv2247, the β subunit of acyl-CoA carboxylase (ACCD6) from Mycobacterium tuberculosis

Mycobacterium tuberculosis (Mtb) acyl-CoA carboxylase is involved in the biosynthesis of mycolic acids, which are a key component of the bacillus cell wall. The Mtb genome encodes six acyl-CoA carboxylase β subunits (ACCD1–6), three of which (ACCD4–6) are essential for survival of the pathogen on mi...

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Bibliographic Details
Main Authors: Niu, Chunying, Yin, Jiang, Cherney, Maia M., James, Michael N. G.
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2011
Subjects:
Crystallization Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232159/
https://ncbi.nlm.nih.gov/pubmed/22139186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111038413
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