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Functional reconstitution of the Mycobacterium tuberculosis long-chain acyl-CoA carboxylase from multiple acyl-CoA subunits

Mycobacterium tuberculosis produces a large number of structurally diverse lipids that have been implicated in the pathogenicity, persistence and antibiotic resistance of this organism. Most building blocks involved in the biosynthesis of all these lipids are generated by acyl-CoA carboxylases (ACCa...

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Bibliographic Details
Published in:FEBS J
Main Authors: Lyonnet, Bernardo Bazet, Diacovich, Lautaro, Gago, Gabriela, Spina, Lucie, Bardou, Fabienne, Lemassu, Anne, Quémard, Annaïk, Gramajo, Hugo
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393044/
https://ncbi.nlm.nih.gov/pubmed/28222482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14046
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