Functional reconstitution of the Mycobacterium tuberculosis long-chain acyl-CoA carboxylase from multiple acyl-CoA subunits

Mycobacterium tuberculosis produces a large number of structurally diverse lipids that have been implicated in the pathogenicity, persistence and antibiotic resistance of this organism. Most building blocks involved in the biosynthesis of all these lipids are generated by acyl-CoA carboxylases (ACCa...

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Veröffentlicht in:FEBS J
Hauptverfasser: Lyonnet, Bernardo Bazet, Diacovich, Lautaro, Gago, Gabriela, Spina, Lucie, Bardou, Fabienne, Lemassu, Anne, Quémard, Annaïk, Gramajo, Hugo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5393044/
https://ncbi.nlm.nih.gov/pubmed/28222482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.14046
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