Učitavanje...
Therapeutic target-site variability in α(1)-antitrypsin characterized at high resolution
The intrinsic propensity of α(1)-antitrypsin to undergo conformational transitions from its metastable native state to hyperstable forms provides a motive force for its antiprotease function. However, aberrant conformational change can also occur via an intermolecular linkage that results in polymer...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
International Union of Crystallography
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3232123/ https://ncbi.nlm.nih.gov/pubmed/22139150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309111040267 |
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