Resistance to maribavir is associated with the exclusion of pUL27 from nucleoli during human cytomegalovirus infection

Select mutations in the human cytomegalovirus (HCMV) gene UL27 confer low-grade resistance to the HCMV UL97 kinase inhibitor maribavir (MBV). It has been reported that the 608-amino acid UL27 gene product (pUL27) normally localizes to cell nuclei and nucleoli, whereas its truncation at codon 415, as...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Hakki, Morgan, Drummond, Coyne, Houser, Benjamin, Marousek, Gail, Chou, Sunwen
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3232008/
https://ncbi.nlm.nih.gov/pubmed/21906628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2011.08.019
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker