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Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration
1. Apremilast is a novel, orally available small molecule that specifically inhibits PDE4and thus modulates multiple pro- and anti-inflammatory mediators, and is currently under clinical development for the treatment of psoriasis and psoriatic arthritis.The pharmacokinetics and disposition of [(14)C...
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Главные авторы: | , , , , , , , , , , , |
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Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
Informa Healthcare
2011
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3231940/ https://ncbi.nlm.nih.gov/pubmed/21859393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2011.604745 |
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