Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration

1. Apremilast is a novel, orally available small molecule that specifically inhibits PDE4and thus modulates multiple pro- and anti-inflammatory mediators, and is currently under clinical development for the treatment of psoriasis and psoriatic arthritis.The pharmacokinetics and disposition of [(14)C...

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Detalhes bibliográficos
Main Authors: Hoffmann, Matthew, Kumar, Gondi, Schafer, Peter, Cedzik, Dorota, Capone, Lori, Kei-Fong, Lai, Gu, Zheming, Heller, Dennis, Feng, Hao, Surapaneni, Sekhar, Laskin, Oscar, Wu, Anfan
Formato: Artigo
Idioma:Inglês
Publicado em: Informa Healthcare 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231940/
https://ncbi.nlm.nih.gov/pubmed/21859393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/00498254.2011.604745
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