Epigenetic CpG Demethylation of the Promoter and Reactivation of the Expression of Neurog1 by Curcumin in Prostate LNCaP Cells

Curcumin (CUR), a major bioactive polyphenolic component from turmeric curry, Curcuma longa, has been shown to be a potent anti-cancer phytochemical with well-established anti-inflammatory and anti-oxidative stress effects. Chromatin remodeling-related epigenetic regulation has emerged as an importa...

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Main Authors: Shu, Limin, Khor, Tin Oo, Lee, Jong-Hun, Boyanapalli, Sarandeep S. S., Huang, Ying, Wu, Tien-Yuan, Saw, Constance L.-L., Cheung, Ka-Lung, Kong, Ah-Ng Tony
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231852/
https://ncbi.nlm.nih.gov/pubmed/21938566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-011-9300-y
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