Small Molecule Inhibition of the Steroid Receptor Coactivators, SRC-3 and SRC-1

Overexpression of steroid receptor coactivator (SRC)-1 and SRC-3 is associated with cancer initiation, metastasis, advanced disease, and resistance to chemotherapy. In most of these cases, SRC-1 and SRC-3 have been shown to promote tumor cell growth by activating nuclear receptor and multiple growth...

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Hlavní autoři: Wang, Ying, Lonard, David M., Yu, Yang, Chow, Dar-Chone, Palzkill, Timothy G., O'Malley, Bert W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2011
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231837/
https://ncbi.nlm.nih.gov/pubmed/22053001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1222
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