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Normobaric hyperoxia protects the blood brain barrier through inhibiting Nox2 containing NADPH oxidase in ischemic stroke

Normobaric hyperoxia (NBO) has been shown to be neuro- and vaso-protective during ischemic stroke. However, the underlying mechanisms remain to be fully elucidated. Activation of NADPH oxidase critically contributes to ischemic brain damage via increase in ROS production. We herein tested the hypoth...

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Main Authors: Liu, Wenlan, Chen, Qingquan, Liu, Jie, Liu, Ke Jian
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3231818/
https://ncbi.nlm.nih.gov/pubmed/22146586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-9912-1-22
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