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Normobaric hyperoxia delays and attenuates early nitric oxide production in focal cerebral ischemic rats

Overproduction of neuronal nitric oxide synthase (nNOS)-derived NO is detrimental during cerebral ischemia. Normobaric hyperoxia (NBO) has been shown to be neuroprotective, extending the therapeutic time window for ischemic stroke, but the mechanism is not fully understood. In the present study, usi...

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Detalhes bibliográficos
Main Authors: Yuan, Zhongrui, Liu, Wenlan, Liu, Baoyi, Schnell, Aaron, Liu, Ke Jian
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930605/
https://ncbi.nlm.nih.gov/pubmed/20633543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.07.010
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