Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke

Matrix metalloproteinase-9 (MMP-9) and NADPH oxidase contribute to blood brain barrier (BBB) disruption after ischemic stroke. We have previously shown that normobaric hyperoxia (NBO) treatment reduces MMP-9 and oxygen free radical generation in ischemic brain. In this study, we tested the hypothesi...

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Autors principals: Liu, Wenlan, Sood, Rohit, Chen, Qingchuan, Sakoglu, Unal, Hendren, Jill, Çetin, Özdemir, Miyake, Minoru, Liu, Ke Jian
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582595/
https://ncbi.nlm.nih.gov/pubmed/18786175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2008.05664.x
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