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ATP inhibits nuclear and mitochondrial type I topoisomerases from human leukemia cells.
Type I topoisomerases have been purified from nuclei and mitochondria of human acute lymphoblastic leukemia cells. Both of these ATP-independent enzymes are actually found to be inhibited by ATP at physiologically significant concentrations. Other adenine nucleotides showed varying effects: ADP inhi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1986
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323147/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3006064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.6.1680 |
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