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Only high-affinity receptors for interleukin 2 mediate internalization of ligand.

Interleukin 2 (IL-2) receptors are expressed on activated T cells and in select T-cell leukemias. Recently, it has been demonstrated that at least two classes of receptor for IL-2 exist with markedly different affinities for ligand. All known biological actions of IL-2 have been correlated with occu...

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Publicado en:Proc Natl Acad Sci U S A
Principais autores: Weissman, A M, Harford, J B, Svetlik, P B, Leonard, W L, Depper, J M, Waldmann, T A, Greene, W C, Klausner, R D
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1986
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC323096/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3081898/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.5.1463
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